|
Classification of CGD subunits. |
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| CGD gene |
Genetic Transmission |
Frequency (%) |
|
|
||
| gp91phox (CYBB) |
X-linked |
65 |
| p47phox (NCF1) |
Autosomal recessive |
25 |
| p67phox (NCF2) |
Autosomal recessive |
5 |
| p22phox (CYBA) |
Autosomal recessive |
5 |
|
Mutations can occur in one of four NADPH oxidase subunits which give rise to X-linked or autosomal recessive CGD. The approximate frequencies of case occurrence are shown, with figures extrapolated from Clark et al. [35] and Dineaur et al.[38]. | ||
Assari Medical Immunology 2006 5:4 doi:10.1186/1476-9433-5-4 |
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